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Benzoyl Peroxide Spot Treatment Comparison - October 2025

1
Best Choice
9.9Exceptional
2
9.8Exceptional
3
9.7Exceptional
4
9.5Excellent
5
Best Value
9.3Excellent
6
9.2Excellent
7
9.0Excellent
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Model

Perrigo 10% Benzoyl Peroxide Acne Treatment Gel 2.1 oz
Model
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, Maximum Strength 10% Benzoyl Peroxide Treatment Medication for Acne Prone Skin, Pimple Cream Reduces Size & Redness in 2 Hours, 1 oz
Model
Paula's Choice CLEAR Daily Skin Clearing Treatment with Benzoyl Peroxide, Treats and Prevents Mild to Severe Acne & Breakouts, Fragrance-Free, 2.25 Fl. Oz.
Model
Amazon Basics 10% Benzoyl Peroxide Acne Medication, Maximum Strength, 1 Fluid Ounce Face Gel
Model
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1
Model
Clean & Clear Persa-Gel 10 Oil-Free Acne Spot Treatment with Maximum Strength 10% Benzoyl Peroxide, Topical Pimple Cream & Gel Medication for Face, Fragrance-Free, 1 fl. oz, 1 Pack
Model
Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

Brand

Perrigo
Brand
Neutrogena
Brand
Paula's Choice
Brand
Amazon Basics
Brand
AcneFree
Brand
Clean & Clear
Brand
Neutrogena

Reviews

6,240 reviews
Reviews
52,062 reviews
Reviews
5,882 reviews
Reviews
4,800 reviews
Reviews
31,802 reviews
Reviews
5,284 reviews
Reviews
2,816 reviews

Features

Worth the money

9.1
Worth the money
8.6
Worth the money
8.6
Worth the money
9.1
Worth the money
8.9
Worth the money
8.1
Worth the money
7.9

Aroma

9.1
Aroma
9.1
Aroma
8.9
Aroma
8.6
Aroma
8.1
Aroma
7.4
Aroma
7.2

Fashion

9.1
Fashion
8.9
Fashion
8.6
Fashion
9.9
Fashion
8.1
Fashion
7.4
Fashion
7.2

Moisturizing

9.1
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0

For gentle skin

9.1
For gentle skin
8.1
For gentle skin
7.9
For gentle skin
8.1
For gentle skin
7.9
For gentle skin
7.2
For gentle skin
7.0

Sheerness

9.1
Sheerness
7.7
Sheerness
7.6
Sheerness
9.1
Sheerness
8.1
Sheerness
7.4
Sheerness
7.2

Tech Specs

product dimensions

-
product dimensions
-
product dimensions
-
product dimensions
0.99 x 1.51 x 4.24 inches 1.45 ounces
product dimensions
4.5 x 1.5 x 3.75 inches 1 ounces
product dimensions
1.1 x 4.6 x 3.8 inches 1 ounces
product dimensions
1.45 x 3.95 x 3.95 inches 1.59 Pounds

Review

Review Review
-
Review Review
-
Review
-
Review
-

Available On

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Our Top 3 Picks

Here are the top 3 recommended products with more information to help you find the right product for you
  • 9.9
    1
    Perrigo
    16% Off

    Perrigo 10% Benzoyl Peroxide Acne Treatment Gel 2.1 oz

    9.1 worth the money
    9.1 Aroma
    9.1 Fashion

    Why we love it

    Fast acne relief
    Gentle on skin
    Visible results
  • 9.8
    2
    Neutrogena
    27% Off

    Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, Maximum Strength 10% Benzoyl Peroxide Treatment Medication for Acne Prone Skin, Pimple Cream Reduces Size & Redness in 2 Hours, 1 oz

    9.1 Aroma
    8.9 Fashion
    8.6 worth the money

    Why we love it

    Rapidly reduces acne size and redness.
    Effective on stubborn, persistent acne.
    Dermatologist-recommended formula.
  • 9.7
    3
    Paula's Choice

    Paula's Choice CLEAR Daily Skin Clearing Treatment with Benzoyl Peroxide, Treats and Prevents Mild to Severe Acne & Breakouts, Fragrance-Free, 2.25 Fl. Oz.

    8.9 Aroma
    8.6 worth the money
    8.6 Fashion

    Why we love it

    Effectively reduces acne and redness.
    Hydrates while treating skin.
    Suitable for all skin types.

Our ranking system

At bestchoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.

Features

Our AI-driven analysis examines key attributes, capabilities, and other critical factors tailored to each product category. This method allows us to assess effectiveness from various perspectives, ensuring a well-rounded evaluation.
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Consumer Reviews

We aggregate and evaluate consumer feedback from across the internet, giving weight to ratings and reviews that reflect the most reliable insights. AI enhances this process by filtering and prioritizing data, offering a balanced view without the need for direct personal endorsements.
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Popularity

Our system also considers the popularity of products, analyzing factors such as market presence, reputation, and user satisfaction. By leveraging AI, we capture a comprehensive picture of a product's standing in the market, which may not always be evident through traditional testing.
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Value for money

AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
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