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Digestive Enzymes Comprehensive Comparison - October 2025

1
Best Choice
9.9Exceptional
2
9.7Exceptional
3
9.6Exceptional
4
9.3Excellent
5
Best Value
9.2Excellent
6
9.0Excellent
7
8.8Very Good
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Model

Purely Optimal Digestive Enzyme Supplement - Comprehensive Gut Health Support with 12 Enzymes, Probiotics & Prebiotics - Relief for Bloating, Gas & Digestive Discomfort - 180 Capsules
Model
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules
Model
MaryRuth Organics Ultra Digestive Enzymes Capsules | Up to 2 Month Supply | Supplement for Gut Health Support | Digestion & Immune Support with Amylase | Lipase & Lactase | Vegan | 60 Count
Model
THORNE - Advanced Digestive Enzymes (Formerly Bio-Gest) - Blend of Digestive Enzymes to Aid Digestion* - Gut Health Support with Pepsin, Ox Bile, Pancreatin - 180 Capsules - 90 Servings
Model
Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 60 CT
Model
Enzymedica Digest Gold + Probiotics, 2-in-1 Formula for Gut Health, Digestive Enzymes & 1.5 Billion Active Probiotic Cultures, 45 Count
Model
Enzymedica Digest Spectrum, Digestive Enzymes for Multiple Food Intolerances, Offers Fast-Acting Gas & Bloating Relief, 30 Count

Brand

Purely Optimal
Brand
Pure Encapsulations
Brand
MaryRuth Organics
Brand
THORNE
Brand
Physician's CHOICE
Brand
Enzymedica
Brand
Enzymedica

Reviews

6,498 reviews
Reviews
6,206 reviews
Reviews
5,478 reviews
Reviews
2,374 reviews
Reviews
11,460 reviews
Reviews
5,034 reviews
Reviews
4,508 reviews

Features

Worth the money

9.8
Worth the money
8.9
Worth the money
9.1
Worth the money
8.6
Worth the money
8.1
Worth the money
7.9
Worth the money
8.4

Flavor

9.8
Flavor
9.1
Flavor
9.6
Flavor
9.4
Flavor
9.1
Flavor
9.1
Flavor
8.4

Simple to consume

9.9
Simple to consume
9.1
Simple to consume
9.8
Simple to consume
9.4
Simple to consume
9.3
Simple to consume
9.1
Simple to consume
8.6

Tech Specs

product dimensions

10 x 5 x 5 inches 5.29 ounces
product dimensions
3.4 x 1.9 x 1.2 inches 1.4 ounces
product dimensions
-
product dimensions
2.89 x 2.89 x 5.22 inches 7.2 ounces
product dimensions
2.31 x 2.31 x 4.5 inches 2.89 ounces
product dimensions
2.3 x 2.3 x 4.6 inches 0.48 ounces
product dimensions
2 x 2 x 2 inches 1.13 ounces

Review

Review Review Review
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Review
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Review
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Review

Available On

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Our Top 3 Picks

Here are the top 3 recommended products with more information to help you find the right product for you
  • 9.9
    1
    Purely Optimal

    Purely Optimal Digestive Enzyme Supplement - Comprehensive Gut Health Support with 12 Enzymes, Probiotics & Prebiotics - Relief for Bloating, Gas & Digestive Discomfort - 180 Capsules

    9.9 simple to consume
    9.8 worth the money
    9.8 Flavor

    Why we love it

    The product eases discomfort in your system.
    The product promotes better digestion.
    The product has 12 powerful enzymes.
  • 9.7
    2
    Pure Encapsulations

    Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

    9.1 Flavor
    9.1 simple to consume
    8.9 worth the money

    Why we love it

    Improves nutrient absorption.
    Reduces bloating effectively.
    Supports diverse digestive needs.
  • 9.6
    3
    MaryRuth Organics

    MaryRuth Organics Ultra Digestive Enzymes Capsules | Up to 2 Month Supply | Supplement for Gut Health Support | Digestion & Immune Support with Amylase | Lipase & Lactase | Vegan | 60 Count

    9.8 simple to consume
    9.6 Flavor
    9.1 worth the money

    Why we love it

    Vegan and non-GMO formula.
    Supports digestion and nutrient absorption.
    Reduces bloating and abdominal discomfort.

Our ranking system

At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.

Features

Our AI-driven analysis examines key attributes, capabilities, and other critical factors tailored to each product category. This method allows us to assess effectiveness from various perspectives, ensuring a well-rounded evaluation.
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Consumer Reviews

We aggregate and evaluate consumer feedback from across the internet, giving weight to ratings and reviews that reflect the most reliable insights. AI enhances this process by filtering and prioritizing data, offering a balanced view without the need for direct personal endorsements.
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Popularity

Our system also considers the popularity of products, analyzing factors such as market presence, reputation, and user satisfaction. By leveraging AI, we capture a comprehensive picture of a product's standing in the market, which may not always be evident through traditional testing.
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Value for money

AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
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