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Lidocaine 5 Spray Comparison - July 2025

1
Best Choice
9.8Exceptional
2
9.6Exceptional
3
9.3Excellent
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Model

Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.
Model
Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces
Model
Myderm Medical Numbing Spray - 4.5oz - Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel - Fast-Acting Reliever with A Touch-Free Application - First Aid Supplies - Made in USA

Brand

Aspercreme
Brand
Icy Hot
Brand
Myderm

Reviews

48,364 reviews
Reviews
20,884 reviews
Reviews
688 reviews

Review

Review
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Review
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Our Top 3 Picks

Here are the top 3 recommended products with more information to help you find the right product for you
  • 9.8
    1
    Aspercreme

    Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.

    Why we love it

    Numbs tough muscle pain
    Joint pain and back pain
    Fast acting pain relief
    Main highlights
    • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
    • Keeps Hands Clean: Non-greasy Aspercreme pain relief spray dries quickly and works at any angle
    • Fragrance-Free Formula: Aspercreme pain relief dry spray has no odor for discreet pain relief
    • Fast-Acting Relief: Max-strength 4% lidocaine pain relief dry spray targets nerves and numbs away pain
    • Contains one (1) 4-oz. spray bottle of Aspercreme Lidocaine Pain Relief Dry Spray, designed to numb away nerve pain
    • Aspercreme is the #1 topical lidocaine brand in the U.S.*
  • 9.6
    2
    Icy Hot

    Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces

    Main highlights
    • NUMBS AWAY PAIN: Icy Hot Lidocaine Spray desensitizes aggravated nerves to temporarily relieve minor pains associated with back pain, knee pain and muscle pain
    • NO-MESS SPRAY: Continuous spray dries quickly and works at any angle for fast, easy pain relief
    • INCLUDES: One (1) 4-oz. bottle of Icy Hot Max Strength Pain Relief Dry Spray With Lidocaine Plus Menthol
    • FAST ACTING & LONG LASTING: This pain-relieving spray penetrates to the nerves for pain relief at the push of a button
    • AMERICA'S TOPICAL PAIN RELIEVER: Icy Hot is the number-one topical pain relief brand among OTC topical analgesics
  • 9.3
    3
    Myderm

    Myderm Medical Numbing Spray - 4.5oz - Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel - Fast-Acting Reliever with A Touch-Free Application - First Aid Supplies - Made in USA

    Main highlights
    • Paraben Free: It can be difficult to find numbing products that don't contain parabens and fillers, but our formula has been and will always be free from parabens. That means it is safe and formulated not to irritate your skin or cause dryness and discomfort after use.
    • Made in the USA: We manufacture in a licensed and regulated facility in the United States. You can rest assured that our products are safe for you and your family.
    • Innovative Formulas, Affordable Solutions: Our innovative products range from ache ease, first aid, skin care, to anti-aging products. No matter what you're looking for, we want you always to find comfort in myDerm.
    • Get Ahead of discomfort: Experience faster relief, piercing and tattoo numbing, and relief from foot discomfort with myDerm MEDICAL Numbing Spray. Our numbing spray is formulated with 5% Lidocaine, Phenylephrine HCl, and Witch Hazel - ingredients that work together to help temporarily numb and relieve ache from minor burns, skin abrasions, itchy skin, and anorectal conditions.
    • Fast Acting, Touch-Free Application: Our topical lidocaine works fast and penetrates deep into the skin to help soothe swelling and burning. Our rapid topical discomfort sprays at any angle with a touch-free application for hygienic purposes. Great for numbing, piercing and tattoo aftercare, as well as muscle discomfort.

Our ranking system

At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.

Features

Our AI-driven analysis examines key attributes, capabilities, and other critical factors tailored to each product category. This method allows us to assess effectiveness from various perspectives, ensuring a well-rounded evaluation.
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Consumer Reviews

We aggregate and evaluate consumer feedback from across the internet, giving weight to ratings and reviews that reflect the most reliable insights. AI enhances this process by filtering and prioritizing data, offering a balanced view without the need for direct personal endorsements.
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Popularity

Our system also considers the popularity of products, analyzing factors such as market presence, reputation, and user satisfaction. By leveraging AI, we capture a comprehensive picture of a product's standing in the market, which may not always be evident through traditional testing.
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Value for money

AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
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