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Methylated Multivitamin Comparison - September 2025
| 1 Best Choice  9.8Exceptional | 2  9.7Exceptional | 3  9.6Exceptional | 4 Best Value  9.5Excellent | 5  9.4Excellent |
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ModelMethyl Multi Without Iron Methylated Multivitamin for Men & Women, 120-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 240 Caps | Model 10X Health Optimize Methylated Multivitamin - 90 Capsules, 34 in 1 Formula with 800 mcg of Vitamin B12 - Methylated Multivitamin for Men & Women with 5-MTHF, NAC, Methyl B Complex - MTHFR Supplement | Model envitamin Methylated Multivitamin Multimineral Complex L Methylfolate | Model Micro Ingredients Pure Methylated Multivitamin, 240 Capsules | 19-in-1 Formula with Vitamins C, D, B12, Folate, Magnesium, Zinc & More | Supports Daily Wellness & Immune Health | Filler Free, Non-GMO | Model Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood |
BrandPure Therapro Rx | Brand 10X Health System | Brand envitamin | Brand Micro Ingredients | Brand Double Wood Supplements |
Reviews | Reviews | Reviews | Reviews  | Reviews |
Tech Specs | ||||
package dimensions- | package dimensions 4.29 x 2.2 x 2.13 inches 3.53 ounces | package dimensions 4.21 x 1.81 x 1.73 inches 0.8 ounces | package dimensions 5.28 x 2.68 x 2.64 inches 5 ounces | package dimensions - |
Review | Review - | Review - | Review - | Review - |
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Our Top 3 Picks
Here are the top 3 recommended products with more information to help you find the right product for you
9.8
1Pure Therapro RxMethyl Multi Without Iron Methylated Multivitamin for Men & Women, 120-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 240 Caps
Why we love it
Vegan-friendly and hypoallergenic formula.
Supports energy and cognitive function.
No artificial ingredients or fillers.
Main highlights- 𝐎𝐏𝐓𝐈𝐌𝐀𝐋 𝐀𝐁𝐒𝐎𝐑𝐏𝐓𝐈𝐎𝐍: When supplementing, absorption is key! Methyl Multi without Iron is formulated with Quatrefolic Folate (5-MTHF), Albion TRAACS mineral chelates, and other micronutrients in their pre-methylated and coenzyme forms for optimal absorption and bioavailability, all together in patented EMBOCAPS AP60 acid resistant vegetable capsules designed for a guaranteed 60 minutes of acid-protection.
- 𝐍𝐎 𝐀𝐑𝐓𝐈𝐅𝐈𝐂𝐈𝐀𝐋 𝐈𝐍𝐆𝐑𝐄𝐃𝐈𝐄𝐍𝐓𝐒: Pure TheraPro Rx Methyl Multi without Iron contain no fillers such as rice flour, cornstarch, or wood pulp fibers. Our manufacturing facility adheres to strict NSF/cGMP guidelines. Consumer safety and satisfaction are our highest priority, which is why our products undergo rigorous third-party testing and screening to ensure product purity and potency.
- 𝐍𝐄𝐖 𝐓𝐎 𝐌𝐄𝐓𝐇𝐘𝐋𝐀𝐓𝐈𝐎𝐍? For those extremely sensitive or new to methylated vitamins, we recommend gradually increasing the amount you are taking so your body can adapt. A small percentage of customers can experience a temporary detoxification / Herxheimer response. Symptoms may include: headache, lethargy, skin rash / hives, respiratory symptoms (cough, sore throat). These are temporary and a sign that the supplement is working. However if your body detoxes too quickly at one time it can overload your detox pathways! It’s imperative to lower the amount you are taking for a few days and work your way up slowly to the full dose “LOW & SLOW”
- 𝐄𝐋𝐄𝐕𝐀𝐓𝐄 𝐓𝐎𝐓𝐀𝐋 𝐖𝐄𝐋𝐋𝐍𝐄𝐒𝐒: Discussed on The Joe Rogan Experience with Gary Brecka, our Methyl Multi without Iron is a vegan-friendly, hypoallergenic, and meticulously-researched multivitamin and multimineral supplement made from high-quality ingredients with zero fillers. Our comprehensive formulation promotes healthy cognitive function and supports antioxidant protection and detoxication. Methyl Multi is the ultimate multivitamin to support total-body wellness and optimum vitality.
- 𝐂𝐎𝐌𝐏𝐋𝐄𝐓𝐄 𝐌𝐓𝐇𝐅𝐑 𝐒𝐔𝐏𝐏𝐎𝐑𝐓: Millions of Americans have MTHFR and/or COMT mutations, making it difficult for their bodies to process key vitamins like B12 and Folate. Methyl Multi without Iron contains pre-methylated forms of B12 and Folate for increased bioavailability, which can help to support healthy metabolism, energy release from food, detoxification, and nervous system function.
- 𝐀𝐁𝐎𝐔𝐓 𝐔𝐒: Pure TheraPro Rx was founded in Denver Colorado to formulate and manufacture the highest quality supplements available on the market today. Purity is our priority, which is why we insist on using patented, clinically studied ingredients, and never utilizing fillers, flow agents, excipients, or ingredients sourced from China. We also never use dairy, gluten, corn, soy, or other common allergens in any of our class-leading, practitioner-recommended formulas.
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9.7
210X Health System
10X Health Optimize Methylated Multivitamin - 90 Capsules, 34 in 1 Formula with 800 mcg of Vitamin B12 - Methylated Multivitamin for Men & Women with 5-MTHF, NAC, Methyl B Complex - MTHFR Supplement
Why we love it
Supports optimal health and wellness.
Ideal for reducing supplement intake.
Enhances mental focus and clarity.
Main highlights- Vital Minerals for Balance: Formulated with optimized minerals such as magnesium and zinc, this methylated multivitamin for women and men helps to maintain essential mineral balance and support immunity, energy production, and cognitive function.
- Targeted Nutritional Support: 10X Optimize methylated multivitamin offers the ultimate methylated B vitamins and mineral formulated to address genetic deficits in your methylation pathway. This impacts your overall wellness and supports optimal health.
- Quality and Safety Focused: The 10X Optimize methylated multivitamin from 10X Health System is proudly made in the USA using premium, carefully sourced ingredients. Each batch undergoes rigorous quality and purity testing, ensuring your wellness.
- Essential Methylated Nutrients: This includes methylated vitamins like 5-MTHF plus methyl B12 (methylfolate), and Methyl B complex, such as riboflavin (B2), and pyridoxine (B6). This MTHFR Supplement supports your body's natural methylation processes.
- Additional Methylation Support: Contains NAC (N-acetyl L-cysteine), a powerful amino acid known for its excellent support of the methylation pathway. NAC helps boost your body's ability to boost antioxidant levels and promote cellular health.
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9.6
3envitamin
envitamin Methylated Multivitamin Multimineral Complex L Methylfolate
Why we love it
Contains essential micronutrients.
Boosts energy and wellness.
Ideal for active individuals.
Main highlights- Methylated Multivitamin Complex By envitamin with L Methylfolate
- Methylated B12, 5-MTHF, Inositol, & Lycopene
- Contains the micronutrients you need for your body
Our ranking system
At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.
Features
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Value for money
AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
