Nad Supplement Comparison - August 2025

Our Top 3 Picks
Here are the top 3 recommended products with more information to help you find the right product for you9.7
1TRU NIAGENTRU NIAGEN Patented NAD+ Supplement for Anti Aging and Cell Regeneration, 300 mg Niagen, 30 Servings | Supports Cellular Energy, Brain, Muscle | Nicotinamide Riboside (NR) Take 1 Daily | 1 Bottle
Why we love it
Clinically proven to boost NAD+ levels.
Enhances energy and vitality.
Supports healthy aging processes.
Main highlights- VITAL FOR CELLULAR ENERGY – Tru Niagen supports your ability to stay healthy by boosting NAD+ levels, which naturally decline as you age. NAD+ is vital for cells to function and repair. It supports brain health, muscle health and recovery, heart health, cellular energy and repair, and lifestyle stress management. Patented Tru Niagen is more efficient at raising NAD+ than other NAD+ precursors such as NMN, niacinamide, or niacin.
- TRU STORY: WITHOUT NAD, CELLS DIE. Our bodies naturally decrease in NAD+, with up to 65% decline between ages 30-70. Effects of metabolic stress and time can accelerate aging, which leads to many health concerns. Most clinical studies have used 1000mg daily. NAD+ decline begins in your 30s, it's recommended to start with 300mg daily. As you age and are exposed to more metabolic stressors, you can move to 1000mg daily. Always check with your healthcare provider for the best dose for you.
- TESTED FOR SAFETY, POTENCY, AND PURITY – Tru Niagen is one of the most well-studied, patented, supplements. Our patented ingredient Niagen has achieved regulatory acceptance by the US FDA for use in supplements: twice as an NDI (New Dietary Ingredient), and once as GRAS (Generally Recognized As Safe). Every batch is made in the United States with globally sourced ingredients and third-party tested by ISO/IEC accredited labs for potency, safety, and purity. Tru Niagen NAD+ capsules are vegetarian, gluten free, nut free, caffeine free, and have no artificial flavors or colors.
- SUPPORTED BY DECADES OF RESEARCH – Tru Niagen is one of the most well-researched patented supplements and is backed by two Nobel Prize winners, 50 owned and licensed patents, 400+ published scientific studies, 275+ global research collaborations, and 30+ clinical trials. Supported by decades of science and research, Tru Niagen is truly one-of-a-kind.
- A COMPLETE ANTI AGING SUPPLEMENT – Support whole body wellness and boost energy with Tru Niagen, a patented NAD plus supplement which supports the 37.2 trillion cells in your body and its production of nicotinamide riboside (NR) to promote healthy cell activity and reduce aging-related health concerns. Tru Niagen is clinically proven to be one of the safest and most efficient boosters of NAD+ levels, with an average increase of over 50% in 2 weeks with daily use
9.6
2Cata-Kor11% OffNMN Supplement Alternative - Liposomal NAD with Resveratrol - High Purity NAD Supplement for Anti-Aging, Energy, Focus - 60 Capsules
Why we love it
Boosts energy and mental clarity.
Enhances absorption with liposomal delivery.
Supports healthy aging and recovery.
Main highlights- TESTED IN THE USA: Our NAD, Resveratrol supplement is third-party tested in the USA to ensure its purity and effectiveness. Certificate available upon request. Get back to feeling your best with NAD+ supplement booster today.
- SUPPORTS SKIN AGING with Liposomal NAD, Resveratrol, an NMN supplement alternative that enhances your body's absorption and utilization of NAD precursors
- INCREASE ABSORPTION BY 9.3x: Maximize bioavailability with our Liposomal NAD encapsulation technology – 9.3 times more effective than competitors.
- FEEL YOUTHFUL AGAIN: With daily dose of our Liposomal NAD capsules with Resveratrol, you'll get a unique blend that supports healthy skin aging, energy production, focus and longevity.
9.4
3Life Extension26% OffLife Extension NAD+ Cell Regenerator and Resveratrol Elite, NIAGEN nicotinamide riboside, Trans-resveratrol, quercetin, Fisetin, for Longevity, Energy, and oxidative Stress, 30 Vegetarian Capsule
Why we love it
Boosts cellular energy levels effectively.
Supports youthful cognitive function.
Enhances heart health and reduces oxidative stress.
Main highlights- More bioavailable formula – The trans-resveratrol, quercetin and fisetin in this formula are combined with fenugreek fibers to increase bioavailability compared to traditional nutrients.
- Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
- Ingredients matter – We use only the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Healthy aging & energy support – Resveratrol protects cells from oxidative stress and encourages healthy aging, while nicotinamide riboside provides energy pathway support.
- Complementary nutrients – This formula delivers 300 mg of nicotinamide riboside, bioavailable trans-resveratrol, and quercetin and fisetin for complementary health-promoting benefits.
Nad Supplement Buyer's Guide

Intro to NAD Supplement
NAD stands for nicotinamide adenine dinucleotide, and is a coenzyme found in all living cells. NAD helps regulate the energy in cells, and is essential for cells to perform their metabolic activities. NAD supplements are becoming increasingly popular as they are thought to help improve energy levels, mental clarity, and even help slow down the aging process. In this buying guide, we will explore the different types of NAD supplement available, their benefits, and how to choose the best one for you.
Types of NAD Supplement
NAD supplements come in two main forms, NADH and NR. NADH is the active form of NAD, and helps to increase energy levels, boost mental clarity and focus, and even help to improve sleep quality. NR is a precursor to NADH and helps to improve energy levels and cognitive performance. NADH supplements are generally taken in powder form, whereas NR supplements are usually found in tablet form.
Benefits of NAD Supplement
NAD supplements can have a range of benefits. By providing your body with a higher concentration of NAD, you can help to improve energy levels, mental clarity, and focus. NAD supplements are also thought to help slow down the aging process, as it helps to regulate the energy in cells. Additionally, NAD supplements can help to improve sleep quality, as it helps to regulate the body’s circadian rhythm.

Choosing the Right NAD Supplement
When choosing the right NAD supplement, it’s important to consider your individual needs and goals. If you’re looking for a supplement to help improve energy levels and focus, then NADH is likely the better option for you. If you’re looking for a supplement to help improve energy levels and cognitive performance, then NR may be the better choice. Additionally, it’s important to consider the form in which you would like to take the supplement, as NADH is generally found in powder form, whereas NR is found in tablet form.
Side Effects of NAD Supplement
When taken in recommended doses, NAD supplements are generally considered safe and well-tolerated. However, some people may experience side effects such as headaches, nausea, and dizziness. It’s important to speak to your doctor before taking any NAD supplement, and to follow the instructions on the label.
Conclusion
NAD supplements can be beneficial in helping to improve energy levels, mental clarity, and focus. There are two main forms of NAD supplement available, NADH and NR, and it’s important to consider your individual needs and goals when choosing the right one for you. Additionally, it’s important to speak to your doctor before taking any NAD supplement, and to follow the instructions on the label.

Our ranking system
At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.