Advertising Disclosure

Otc Acne Treatment Comparison - July 2025

1
Best Choice
9.9Exceptional
2
9.7Exceptional
3
9.6Exceptional
4
9.3Excellent
5
Best Value
9.1Excellent
6
9.0Excellent
View DealOn Amazon
View DealOn Amazon
View DealOn Amazon
View DealOn Amazon
View DealOn Amazon
View DealOn Amazon

Model

Proactiv 3 Step Acne Treatment - Benzoyl Peroxide Face Wash, Repairing Acne Spot Treatment for Face and Body, Exfoliating Toner - 30 Day Complete Acne Skin Care Kit
Model
Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)
Model
Differin Acne Face Wash with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Foaming Cleanser, Fast Acting Acne Treatment for Face and Body, 5 oz.
Model
Differin Acne Spot Treatment with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Treatment, Fast Acting Spot Treatment for Face, 1 oz
Model
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1
Model
Neutrogena On-The-Spot Acne Treatment Gel with Benzoyl Peroxide - Gentle Face Acne Medicine for Acne Prone Skin, 0.75 oz

Brand

Proactiv
Brand
Differin
Brand
Differin
Brand
Differin
Brand
AcneFree
Brand
Neutrogena

Reviews

188,488 reviews
Reviews
315,588 reviews
Reviews
920 reviews
Reviews
8 reviews
Reviews
63,604 reviews
Reviews
5,632 reviews

Features

Worth the money

8.6
Worth the money
8.6
Worth the money
8.6
Worth the money
8.4
Worth the money
8.9
Worth the money
8.1

Aroma

7.9
Aroma
8.6
Aroma
8.4
Aroma
8.1
Aroma
8.1
Aroma
7.4

Moisturizing

7.9
Moisturizing
7.2
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0
Moisturizing
7.0

For gentle skin

8.1
For gentle skin
7.9
For gentle skin
7.7
For gentle skin
7.6
For gentle skin
7.9
For gentle skin
7.2

Tech Specs

product dimensions

11.25 x 7.5 x 2.25 inches 11.68 ounces
product dimensions
1.5 x 2.1 x 6.5 inches 0.48 ounces
product dimensions
-
product dimensions
-
product dimensions
4.5 x 1.5 x 3.75 inches 1 ounces
product dimensions
1.45 x 3.95 x 3.95 inches 1.59 Pounds

Review

-
Review Review
-
Review
-
Review
-
Review
-

Available On

Available On Available On Available On Available On Available On

Our Top 3 Picks

Here are the top 3 recommended products with more information to help you find the right product for you
  • 9.9
    1
    Proactiv

    Proactiv 3 Step Acne Treatment - Benzoyl Peroxide Face Wash, Repairing Acne Spot Treatment for Face and Body, Exfoliating Toner - 30 Day Complete Acne Skin Care Kit

    8.6 worth the money
    8.1 For Gentle skin
    7.9 Aroma

    Why we love it

    Targets acne deeply and prevents future breakouts.
    Simple 3-step routine for clear, radiant skin.
    Effective for all ages and sensitive skin types.
  • 9.7
    2
    Differin

    Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

    8.6 worth the money
    8.6 Aroma
    7.9 For Gentle skin

    Why we love it

    Reduces acne breakouts effectively.
    Improves skin texture and tone.
    Suitable for acne-prone sensitive skin.
  • 9.6
    3
    Differin
    21% Off

    Differin Acne Face Wash with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Foaming Cleanser, Fast Acting Acne Treatment for Face and Body, 5 oz.

    8.6 worth the money
    8.4 Aroma
    7.7 For Gentle skin

    Why we love it

    Fast-acting acne treatment.
    Effective on face and body.
    Improves skin texture.

Our ranking system

At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.

Features

Our AI-driven analysis examines key attributes, capabilities, and other critical factors tailored to each product category. This method allows us to assess effectiveness from various perspectives, ensuring a well-rounded evaluation.
smartphone

Consumer Reviews

We aggregate and evaluate consumer feedback from across the internet, giving weight to ratings and reviews that reflect the most reliable insights. AI enhances this process by filtering and prioritizing data, offering a balanced view without the need for direct personal endorsements.
checklist

Popularity

Our system also considers the popularity of products, analyzing factors such as market presence, reputation, and user satisfaction. By leveraging AI, we capture a comprehensive picture of a product's standing in the market, which may not always be evident through traditional testing.
smartphone-stars

Value for money

AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
checklist