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Topical Anesthetic Comparison - July 2025

1
Best Choice
9.8Exceptional
2
9.7Exceptional
3
Best Value
9.4Excellent
4
9.2Excellent
5
9.1Excellent
6
8.9Very Good
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Model

Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)
Model
HurriCaine Topical Anesthetic Gel Watermelon - 1 oz.
Model
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.
Model
Dynamic Dental Candi Caine, Topical Anesthetic Gel, 1 oz, Bubble Gum Flavor
Model
HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
Model
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic

Brand

Curist
Brand
Wuiil
Brand
Aspercreme
Brand
The Essentials
Brand
HealthWise
Brand
HealthWise

Reviews

10,707 reviews
Reviews
4,014 reviews
Reviews
26,667 reviews
Reviews
1,773 reviews
Reviews
60 reviews
Reviews
219 reviews

Tech Specs

product dimensions

3 x 6.5 x 1.75 inches 6 ounces
product dimensions
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product dimensions
2.95 x 1.75 x 6 inches 4.3 ounces
product dimensions
0.6 x 1.1 x 2.1 inches 1.13 ounces
product dimensions
3 x 2 x 5 inches 3.88 ounces
product dimensions
-

Review

Review
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Review Review
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Review
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Review
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Available On

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Our Top 3 Picks

Here are the top 3 recommended products with more information to help you find the right product for you
  • 9.8
    1
    Curist

    Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)

    Why we love it

    Strongest lidocaine available OTC.
    Effective for various skin irritations.
    Non-greasy and easy to apply.
  • 9.7
    2
    Wuiil

    HurriCaine Topical Anesthetic Gel Watermelon - 1 oz.

    Why we love it

    Quickly numbs oral discomfort.
    Easy to apply before procedures.
    Pleasant watermelon flavor.
  • 9.4
    3
    Aspercreme
    34% Off

    Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

    Why we love it

    Numbs pain quickly and effectively.
    No odor or greasy residue.
    Ideal for arthritis and muscle pain.
    Main highlights
    • Travel-Size: Take your pain relief solution on the go in a compact and portable tube
    • Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
    • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
    • Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
    • Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
    • Aspercreme is the topical lidocaine brand in the U.S.

Our ranking system

At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.

Features

Our AI-driven analysis examines key attributes, capabilities, and other critical factors tailored to each product category. This method allows us to assess effectiveness from various perspectives, ensuring a well-rounded evaluation.
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Consumer Reviews

We aggregate and evaluate consumer feedback from across the internet, giving weight to ratings and reviews that reflect the most reliable insights. AI enhances this process by filtering and prioritizing data, offering a balanced view without the need for direct personal endorsements.
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Popularity

Our system also considers the popularity of products, analyzing factors such as market presence, reputation, and user satisfaction. By leveraging AI, we capture a comprehensive picture of a product's standing in the market, which may not always be evident through traditional testing.
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Value for money

AI allows us to compare products based on attributes like price, specifications, and user feedback, helping to determine their value for money. This data-driven approach offers an efficient and reliable way to assess how products stack up against one another in terms of cost-effectiveness.
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