Topical Anesthetic Comparison - July 2025
Our Top 3 Picks
Here are the top 3 recommended products with more information to help you find the right product for you9.8
1CuristCurist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)
Why we love it
Strongest lidocaine available OTC.
Effective for various skin irritations.
Non-greasy and easy to apply.
9.7
2WuiilHurriCaine Topical Anesthetic Gel Watermelon - 1 oz.
Why we love it
Quickly numbs oral discomfort.
Easy to apply before procedures.
Pleasant watermelon flavor.
9.4
3Aspercreme34% OffAspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.
Why we love it
Numbs pain quickly and effectively.
No odor or greasy residue.
Ideal for arthritis and muscle pain.
Main highlights- Travel-Size: Take your pain relief solution on the go in a compact and portable tube
- Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
- Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
- Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
- Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
- Aspercreme is the topical lidocaine brand in the U.S.
Our ranking system
At BestChoice.com, our team curates a selection of top products from a vast array available online, using a sophisticated ranking system based on carefully defined criteria.While traditional hands-on testing has its merits, our use of AI technology offers distinct advantages. AI allows us to process and analyze vast amounts of data from multiple sources, providing a comprehensive view that goes beyond what manual testing can achieve. This approach enables us to deliver insights that are aligned with current trends and consumer preferences, ensuring our reviews are both relevant and up-to-date.